Synthesis of New Coumarin Scaffold Bearing 2-Iminochromene Moiety
نویسندگان
چکیده
Coumarin is classified as one of interesting therapeutic starting research points to obtain remarkable compounds with high efficacy. So, during this research, new 2-iminochromene derivatives bearing coumarin moiety were synthesized. At first, cyanoacetohydrazone 3-acetylcoumarin was prepared and used the material. The synthesized through ring closure derivative 4-hydroxysalicylaldehyde, 5-aryldiazosalicylaldehydes, 2-hydroxynaphthaldehyde 7-hydroxychromone-6-carboxaldehyde derivative. All newly obtained in excellent yields; so, will participate enrichment chemical libraries.
منابع مشابه
Coumarin derivatives bearing benzoheterocycle moiety: synthesis, cholinesterase inhibitory, and docking simulation study
Objective(s): To investigate the efficiency of a novel series of coumarin derivatives bearing benzoheterocycle moiety as novel cholinesterase inhibitors. Materials and Methods: Different 7-hydroxycoumarin derivatives were synthesized via Pechmann or Knoevenagel condensation and conjugated to different benzoheterocycle (8-hydroxyquinoline, 2-mercaptobenzoxazole or 2-mercaptobenzimidazole) using ...
متن کاملCoumarin derivatives bearing benzoheterocycle moiety: synthesis, cholinesterase inhibitory, and docking simulation study
OBJECTIVES To investigate the efficiency of a novel series of coumarin derivatives bearing benzoheterocycle moiety as novel cholinesterase inhibitors. MATERIALS AND METHODS Different 7-hydroxycoumarin derivatives were synthesized via Pechmann or Knoevenagel condensation and conjugated to different benzoheterocycle (8-hydroxyquinoline, 2-mercaptobenzoxazole or 2-mercaptobenzimidazole) using di...
متن کاملSynthesis and In Vitro Antimicrobial Evaluation of New 1,3,4-Oxadiazoles Bearing 5-Chloro-2-methoxyphenyl Moiety
A series of new 1,3,4-oxadiazole derivatives, 4(a-h), containing 5-chloro-2-methoxy benzohydrazide moiety were synthesized by the reaction of 5-chloro-2-methoxybenzoate with different aromatic carboxylic acids. These newly synthesized compounds were characterized by FT-IR, (1)H NMR, mass spectra, and also by elemental analysis. All the newly synthesized compounds were screened for their antibac...
متن کاملSynthesis and Antimicrobial Activity of Some New Nitrogen Heterocyclic Systems Bearing 1, 2, 4-Tiazine Moiety
Attribution-Noncommercial 3.0 Unported License http://creativecommons.org/licenses/by-nc/3.0/), permitting all non commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Global Journal of Science Frontier Research Chemistry Volume 12 Issue 5 Version 1.0 Year 2012 Type : Double Blind Peer Reviewed International Research Journal Publisher: Glob...
متن کاملSynthesis and characterization of some new thiazolidinones containing coumarin moiety and their antimicrobial study
A series of novel thiazolidinones have been synthesized by reaction of various Schiff bases of coumarin with thioglycolic acid. The reaction of 4-hydroxy coumarin with POCl3 yielded 4chloro coumarin 2 and 4-chloro-3, 4', 3', 4"-tercoumarin 2a. Compound 2 was reacted with pphenylene diamine to yield 4-[(4-aminophenyl)amino]-2H-chromen-2-one.Various Schiff bases of coumarin were synthesized by co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chimica Slovenica
سال: 2023
ISSN: ['1318-0207', '1580-3155']
DOI: https://doi.org/10.17344/acsi.2023.8016